Hieronder is het overzicht te vinden welke projecten van het programma DoelmatigheidsOnderzoek aansluiten bij een richtlijnmodule. Het gaat hier om:
- lopende projecten van het programma Doelmatigheidsonderzoek t/m ronde 2020
- afgeronde projecten van het programma Doelmatigheidsonderzoek na 2011
- richtlijnen gepubliceerd op de Richtlijnendatabase t/m mei 2020
Het overzicht wordt twee keer per jaar herzien.
Bekijk ook de bijbehorende publicatie:
Overzicht van projecten – onderzoeksresultaten opgenomen in richtlijn
Een samenwerking van:
Overzicht onderzoek en richtlijnen
Inhoud
- Anesthesiologie (NVA)
- Cardiologie (NVVC)
- Dermatologie en Venereologie (NVDV)
- Heelkunde (NVvH)
- Interne Geneeskunde (NIV)
- Keel-, Neus- en Oorheelkunde (NVKNO)
- Kindergeneeskunde (NVK)
- Klinische Geriatrie (NVKG)
- Longziekten en Tuberculose (NVALT)
- Maag, Darm en Lever (NVMDL)
- Neurochirurgie (NVvN)
- Neurologie (NVN)
- Obstetrie en Gynaecologie (NVOG)
- Oogheelkunde (NOG)
- Orthopedie (NOV)
- Psychiatrie (NVvP)
- Radiologie (NVvR)
- Radiotherapie en Oncologie (NVRO)
- Reumatologie (NVR)
- Revalidatiegeneeskunde (VRA)
- Urologie (NVU)
Overzicht bijgewerkt t/m oktober 2021
Anesthesiologie (NVA)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 843001607 | Delirium in Elderly Patients with Trauma of the Hip - DEPTH-Project | Proximale femurfracturen | Anesthesiologisch beleid femurfractuur > Preoperatieve anesthesiologie femurfractuur |
| 837004020 | Routine posTsuRgical Anesthesia visit to improve patient outComE (TRACE study) | Het perioperatieve proces | Postoperatief traject > Organisatie van zorg postoperatief |
| 171102009 | Remifentanil patient-controlled analgesia (RPCA) vs epidural analgesia (EA) during labour | Medicamenteuze pijnbehandeling bevalling | Epidurale pijnbehandeling bevalling |
| 170885603 | A randomised controlled trial in the palliative setting regarding off-label medication: investigating the efficiency of amitriptyline versus pregabalin from a societal perspective | Pijn bij kanker | Symptomatische behandeling pijn bij kanker > Medicamenteuze behandelingen pijn bij kanker > Epidurale/intrathecale technieken pijn kanker |
Cardiologie (NVVC)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 843001702 | OPTICARE-XL; effectiveness and cost-effectiveness of a novel tailor-made cardiac rehabilitation program for obese patients with coronary artery disease | Hartrevalidatie | Hartrevalidatie bijzondere diagnosegroepen |
| 837001003 | Effects of home-based training with telemonitoring guidance in low to moderate risk patients with an acute coronary syndrome or coronary revascularization | Hartrevalidatie | Interventies bij hartrevalidatie > Interventies gericht op fysieke doelen |
Dermatologie en Venereologie (NVDV)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852101062 | Dose reduction of the new generation biologics (IL17 and IL23 inhibitors) in psoriasis: A pragmatic, multicentre, randomized, controlled, non-inferiority study (BeNeBio study) | Psoriasis | Systemische therapieën |
| 852001928 | (Cost)-effectiveness of optical coherence tomography versus regular punch biopsy in the diagnosis and subtyping of basal cell carcinoma: a multi-center randomized non-inferiority trial | Basaalcelcarcinoom | Diagnostiek BCC |
| 843001601 | In vivo reflectance confocal microscopy, a novel non-invasive tool for diagnosing skin cancer - a randomized controlled trial | Basaalcelcarcinoom | Diagnostiek BCC |
| 837002521 | Single Ambulatory Phlebectomy versus endovenous Thermal Ablation with concomitant ambulatory Phlebectomies: SAPTAP study | Veneuze pathologie/ Varices | Varices -behandeling van zijtakvarices |
Heelkunde (NVvH)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852002123 | Does Increasing Oxygen Nurture Your Symptomatic Ischaemic Ulcer Sufficiently? (DIONYSIUS trial) | Diabetische voet | Behandeling > hyperbare zuurstoftherapie |
| 852002104 | Comparing Negative Pressure Wound Therapy with Instillation vs Standard wound care to treat postoperative wound infections. | Wondzorg | Wondmateriaal voor een geïnfecteerde wond |
| 852002004 | Paravertebral catheter versus Epidural analgesia in Minimally Invasive Esophageal Resection: a randomized controlled multicenter trial (PEPMEN trial) | Oesofaguscarcinoom | Specifieke perioperatieve maatregelen > Analgesie |
| 852002023 | Cost-effectiveness and effectiveness of rubber band ligation versus sutured mucopexy versus haemorrhoidectomy in patients with recurrent haemorrhoidal disease: a multicentre, randomized controlled trial | Proctologie | 1. Behandelalgoritme symptomatische hemorroïden > Graad 1, 2 (en 3) symptomatische hemorroïden 2. Behandelalgoritme symptomatische hemorroïden > Graad 3 en 4 symptomatische hemorroïden |
| 852001903 | Hernia Exploration oR Not In Infants Analysis (HERNIIA-trial): A randomized controlled trial to study the effectiveness and cost-effectiveness of contralateral surgical exploration during unilateral inguinal hernia repair in children. | Liesbreuk bij kinderen | Behandeling bij kinderen met een liesbreuk |
| 852001904 | Improving the quality of life of patients with breast cancer-related lymphedema by lymphaticovenous anastomosis (LVA): A randomized controlled trial | 1. Borstkanker 2. Lymfoedeem | 1. Nazorg en nacontrole > Signalering en behandeling van gevolgen > Locoregionale gevolgen 2. Conservatieve behandeling lymfoedeem |
| 852001909 | Evaluating the utility of bone grafts in open wedge corrective osteotomy and plate fixation in patients with malunited distal radius fractures (WOPPeR trial) | Distale radius fractuur | Chirurgische behandeling van radiusfractuur > Indicatie botvullers bij radiusfractuur |
| 852001926 | The TRIASSIC study: Multicentre, randomised controlled trial comparing TRansanal minimal InvAsive Surgery (TAMIS) and endoscopic Submucosal dIsseCtion (ESD) for resection of non-pedunculated rectal lesions | Colorectaal carcinoom | Primaire behandeling rectumcarcinoom |
| 843002822 | Selective rather than routine histopathology after appendicectomy and cholecystectomy | 1. Galsteenlijden 2. Acute appendicitis | 1. Galblaaspoliep & galblaascarcinoom 2. Standaard histopathologisch |
| 843002704 | Pelvic Floor rehabilitation to improve functional Outcome and quality of life after surgery for Rectal CancEr: a randomized controlled trial. FORCE-trial | Colorectaal carcinoom | Nazorg en nacontrole > Darmfunctiestoornissen na RC behandeling |
| 843002705 | ROutine versus on DEmand removal Of the syndesmotic stabilisation screw; a randomized controlled trial (RODEO-trial) | Enkelfracturen | Operatieve behandeling bij enkelfracturen > Behandeling syndesmoseletsels |
| 843002708 | Initial non-operative treatment strategy versus appendectomy treatment strategy for simple appendicitis in children aged 7- 17 years old. APAC study | Acute appendicitis | Behandeling simpele appendicitis |
| 843002607 | iCAN trial. Intrathoracic versus Cervical esophagogastric ANastomosis after minimally invasive esophagectomy for esophageal cancer | Oesofaguscarcinoom | Behandeling > Chirurgische technieken > Anastomose |
| 848015008 | Non-inferiority multicentre randomized controlled trial comparing a short versus a long course of postoperative antibiotic treatment for complex acute appendicitis | Acute appendicitis | Antibiotica bij acute appendicitis > Postoperatieve antibiotica duur |
| 843004104 | Neoadjuvant chemoradiotherapy plus standard surgery versus active surveillance for oesophageal cancer (SANO-trial) | Oesofaguscarcinoom | Behandeling > Chirurgische behandeling > Chirurgisch vs. niet-chirurgisch bij resectabele tumor |
| 843004106 | Proclion - Prospective evaluation of interventions for critical limb ischemia | Perifeer Arterieel Vaatlijden (PAV) | 1. Endovasculair femoropopliteale traject PAV 2. Endovasculair crurale traject PAV |
| 843004108 | The (cost)effectiveness of neoadjuvant FOLFIRINOX versus upfront surgery for (borderline) resectable pancreatic cancer | Pancreascarcinoom | (Neo-)Adjuvante, chemotherapie, radiotherapie of chemoradiotherapie > Neoadjuvante behandeling resectabel pancreascarcinoom |
| 843004109 | Mediastinal staging of non small cell lung cancer by endobronchial and endoscopic ultrasonography with or without additional surgical mediastinoscopy (MEDIASTrial) | Niet kleincellig longcarcinoom | Diagnostiek > Mediastinoscopie |
| 843004110 | Evaluation of continuous monitoring by pulse oximetry without OSA screening vs. perioperative CPAP treatment following OSA screening in patients undergoing bariatric surgery: a multicenter prospective study (POPCORN-study) | Morbide obesitas | Preoperatief beleid bariatrische chirurgie > Longfunctie voor bariatrische chirurgie |
| 843004118 | EFFectiveness of total Extraperitoneal hernia Correction for clinically occulT inguinal hernia (EFFECT trial): a multicenter randomized controlled trial | Liesbreuk bij volwassenen | Indicatie behandeling asymptomatische liesbreuken |
| 843004119 | How effective is follow-up after endovascular treatment of abdominal aortic aneurysms, can we do better? | Aneurysma van de abdominale aorta | Operatieve behandelingen van een AAA |
| 837001407 | The Amsterdam Wrist Rules, A Clinical Decision Rule | Distale radius fractuur | Beeldvormende diagnostiek radiusfractuur |
| 837002403 | Is routine radiography following the initial 2-week follow-up of traumapatients with wrist and ankle fractures necessary? | Distale radius fractuur | Nazorg van distale radius fracturen |
| 837002004 | Scrutinizing (in)efficient use of cholecystectomy: a randomized trial concerning variation in practice | Galsteenlijden | Ongecompliceerde symptomatische galstenen > Behandeling ongecompliceerde galstenen |
| 171102008 | Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH): cost-effectiveness analysis alongside a multicenter randomized clinical trial | Proximale femurfracturen | Optimale techniek proximale femurfractuur > Repositie fractuur collum femoris fractuur |
| 171102025 | Supervised exercise therapy or immediate PTA for intermittent claudication in patients with an iliac artery obstruction - a randomized controlled trial. | Perifeer Arterieel Vaatlijden (PAV) | Behandeling claudicatio intermittens bij PAV |
Interne Geneeskunde (NIV)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 853001116 | Cost-effectiveness and cost-utility of a personalized multimodal orthotic treatment approach to reduce the risk of foot ulcer recurrence in persons with diabetes | Diabetische voet | Preventie > Preventie van voetulcera bij diabetes |
| 852002127 | Ultrasound guided radiofrequency ablation (RFA) as treatment for hyperthyroidism caused by solitary autonomous thyroid nodules. | Schildklierfunctiestoornissen | Therapie thyreotoxicose |
| 843001804 | DIVERS-II: Treating depression in dialysis patients with a tailored eHealth cognitive based treatment: A cluster randomized controlled trial | Palliatieve zorg bij eindstadium nierfalen | Symptomen > Depressie |
| 843004115 | Effectiveness of Continuous Glucose Monitoring versus stepped Care starting with HypoAware, A Web-Based Psychoeducational Intervention, and adding CGM as needed, in Adult Type 1 Diabetes and Impaired Hypoglycemia Awareness: A Randomized Controlled Trial | Diabetes Mellitus | Hypoglykemie > Preventie hypoglykemie bij diabetes mellitus |
| 843004116 | Improvement of quality of life with home dialysis compared to in-centre haemodialysis? The DOMESTICO project | Nierfunctievervangende behandeling | Dialyse of conservatieve behandeling |
| 843002624 | Equally good, with less: Omitting the sentinel node biopsy in clinically node negative early breast cancer patients | Borstkanker | Invasief carcinoom > Regionale behandeling stadium I-II > SWK-biopsie of OKD |
| 837002508 | Cost-effectiveness and cost-utility of at-home infrared temperature monitoring in reducing the incidence of foot ulcer recurrence in patients with diabetes | Diabetische voet | Preventie > Preventie van voetulcera bij diabetes |
| 837001404 | An innovative strategy for diagnostic fundoscopy in diabetes patients reduces care use and costs compared to usual care | Diabetische retinopathie | Screening op diabetische retinopathie |
| 837001406 | HypoBewust: A combined group and online educational program for diabetes patients with hypoglycemia. A cost-effectiveness Randomized Controlled Trial | Diabetes Mellitus | Hypoglykemie > Preventie hypoglykemie bij diabetes mellitus |
| 171002304 | Efficiency, efficacy and costs of guideline-based therapeutic strategies for patients with proven or possible persistent Lyme disease | Lymeziekte | Langdurige behandeling van lymeziekte |
| 1710022081 | Determining the cost-effectiveness of an effective intervention to improve adherence among treatment-experienced HIV-infected patients in the Netherlands | HIV (Humaan immunodeficiëntievirus) | nvt |
Keel-, Neus- en Oorheelkunde (NVKNO)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 837001503 | Economic evaluation of treatment modalities for position dependent obstructive sleep apnea patients | Obstructief slaapapneu (OSA) bij volwassenen | Behandeling van OSA > Behandeling met positietherapie bij OSA |
| 837002522 | What is the clinical and cost effectiveness of endoscopic sinus surgery (ESS) in adult patients with chronic rhinosinusitis with nasal polyps? | Chronische rhinosinusitis (CRS) en neuspoliep | Chirurgische behandeling bij chronische rhinosinusitis en neuspoliepen |
| 837002523 | Cost-effective diagnostic strategies in patients with asymmetrical hearing impairment or unilateral audiovestibular symptoms suspected of vestibular schwannoma | Perceptieve slechthorendheid bij volwassenen | Aanvullende diagnostiek gehoorverlies |
| 171201005 | Response evaluation after chemoradiation for advanced oropharyngeal cancer using PET-CT and MRI | Hoofd-halstumoren | Follow-up behandeling hoofd-halstumoren > Plaats van PET-CT voor respons evaluatie |
Kindergeneeskunde (NVK)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 843002827 | Supplemental oxygen strategies in children with bronchopulmonary dysplasia (BPD) after the neonatal intensive care period: the SOS BPD study | Bronchopulmonale dysplasie (BPD) | Optimale zuurstofsaturatie bij BPD |
| 843002622 | BeNeDuctus Trial | Bronchopulmonale dysplasie (BPD) | Behandeling PDA bij BPD |
| 837001409 | Pediatric pelvic physiotherapy added to conventional treatment of functional constipation in children in primary care | Obstipatie bij kinderen van 0 tot 18 jaar | Niet-medicamenteuze behandeling obstipatie > Fysiotherapie bij obstipatie kind |
| 171101005 | The use of a Real-Time Medication Monitoring system (RTMM) for the improvement of adherence to inhalation corticosteroids in children with asthma | Astma bij kinderen | Klachten bij inhalatiesteroïden ICS |
Klinische Geriatrie (NVKG)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852002126 | Trial-based effectiveness and cost-effectiveness of the Partner in Balance intervention to self-manage mild dementia via blended eHealth psycho-education and behavioural modelling for the care partner coached by a dementia care professional. | Dementie | Organisatie van zorg bij dementie |
| 852002106 | Eerder erbij: een vroege ondersteuning voor mensen met dementie en hun mantelzorgers. The path towards offering timely support for people with dementia and their caregivers. | Dementie | Organisatie van zorg bij dementie |
| 171002502 | An RCT study of (cost)effectiveness of Dementia Care Mapping intervention in nursing home settings | Dementie | Behandeling dementie > Psychosociale non-farmacologische interventie > Gecombineerde interventies bij dementie |
| 152002024 | Quantifying health status in dementia | Dementie | Diagnostiek dementie > Classificatie van dementie |
Longziekten en Tuberculose (NVALT)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 152031005 | Review of docetaxel, gemcitabine, paclitaxel and vinorelbine for the treatment of non-small cell lung cancer | Niet kleincellig longcarcinoom | Systemische behandeling stadium IV NSCLC |
Maag, Darm en Lever (NVMDL)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852002003 | Dedicated MR imaging vs surgical staging of peritoneal carcinomatosis in colorectal cancer patients; a randomised multicenter trial | Colorectaal carcinoom | Diagnostiek > Detectie synchrone metastasen |
| 171201002 | The "I-aid": a new care pathway to improve quality of care and quality of life in ileostomy patients | Colorectaal carcinoom | Organisatie van zorg - Ondersteunende zorg |
| 171201006 | Innovation in health care for patients with Coeliac Disease: a multidisciplinary ICT self-management system | Coeliakie en Dermatitis Herpetiformis | Coeliakie en dermatitis herpetiformis (richtlijn zit als pdf in database) |
| 171001005 | Magnetic resonance imaging in acute appendicitis | Acute appendicitis | Beeldvorming volwassenen - Acute appendicitis |
| 171001006 | I-FABP; small protein with big impact on clinical management of celiac disease | Coeliakie en Dermatitis Herpetiformis | Coeliakie en dermatitis herpetiformis (richtlijn zit als pdf in database) |
| 171002209 | Computer supported CEA surveillance after curative treatment of colorectal cancer | Colorectaal carcinoom | Nazorg en nacontrole - Follow-up |
| 152031006 | Review of irinotecan, oxaliplatin, docetaxel and bevacizumab for the treatment of colorectal and gastric cancer | Colorectaal carcinoom | Adjuvante systemische therapie > Adjuvante chemotherapie coloncarcinoom |
| 152031010 | Review of docetaxel for the treatment of prostate cancer and gemcitabine for the treatment of pancreatic cancer | Prostaatcarcinoom | Castratie-resistent prostaatcarcinoom > Behandeling na androgeen deprivatie therapie > Tweedelijnsbehandeling mCRPC |
Neurochirurgie (NVvN)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852101065 | Survival and Quality of Life after Early Surgical Intervention versus Wait-and-See in Elderly patients with a Traumatic Acute Subdural Hematoma: a pragmatic randomized controlled trial with multicentre parallel group design (RESET ASDH study). | Herseninfarct en hersenbloeding | Acute behandeling bij hersenbloeding |
| 843002806 | Is endoscopic trans-sphenoidal selective adenoma resection superior and cost-effective compared to medical treatment with cabergoline? A cohort multiple randomized controlled trial for treatment of microprolactinomas | Hypofysechirurgie | Startpagina |
| 843002604 | Cost-effectiveness of posterior cervical foraminotomy(FOR) versus anterior cervical discotomy with fusion (ACDF) for cervical soft/osteophytic disc disease. A randomized controlled multicenter study | Cervicaal radiculair syndroom tgv cHNP | Anterieure behandelingen crs tgv cHNP > Cervicale anterieure discectomie bij crs |
Neurologie (NVN)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852001906 | Cost-effectiveness of lower extremity nerve decompression surgery in diabetic subjects | Pijnlijke diabetische neuropathie (PDNP) | Niet-medicamenteuze behandeling PDNP |
| 843001701 | The PLUS Study: Preventing LUmbar disc Surgery | Lumbosacraal radiculair syndroom | 1. Conservatieve behandeling van LRS > Effectiviteit van steroïdinjecties bij LRS 2. Conservatieve behandeling van LRS > Effectiviteit van fysiotherapie bij LRS |
| 843004107 | Carotid endarterectomy or optimized medical therapy in patients with symptomatic carotid artery stenosis: a cost effectiveness analysis | Herseninfarct en hersenbloeding | Carotisendarteriëctomie bij herseninfarct > Indicaties voor carotisendarteriëctomie |
| 843004113 | The optimal and cost effective approach of transthoracic echocardiography in ischemic stroke or TIA of undetermined cause | Herseninfarct en hersenbloeding | Diagnostiek bij herseninfarct/-bloeding > Cardiale emboliebron herseninfarct |
| 843004117 | Cost-effectiveness of specialized nursing interventions for patients with Parkinson’s disease | Parkinson | Niet-medische behandeling ZvP > Effectiviteit Parkinsonverpleegkundige |
| 843004122 | Klinische en kosteneffectiviteit van gerichte nazorg voor patiënten met mogelijke cognitieve en emotionele klachten na een TIA of kleine beroerte, die rechtstreeks uit het ziekenhuis naar huis ontslagen kunnen worden | Herseninfarct en hersenbloeding | Revalidatie na herseninfarct/-bloeding > Cognitieve revalidatie na herseninfarct |
| 837004005 | Long term follow-up, cost effectiveness and budget impact analysis in patients randomised in a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in The Netherlands – The Mr Clean study | Herseninfarct en hersenbloeding | Reperfusietherapie voor acute herseninfarct > Endovasculaire behandeling herseninfarct |
| 837004013 | Percutaneous transforaminal endoscopic discectomy vs. open microdiscectomy for patients with lumbar disc herniation | Lumbosacraal radiculair syndroom | Invasieve behandeling van LRS > Operatietechnieken voor LRS |
| 837004025 | The Dutch Injection versus Surgery TRIal in CTS patients (DISTRICTS): a multi-center randomized controlled trial comparing two treatment strategies | CTS | 1. Behandeling van CTS 2. Corticosteroïd-injectie bij behandeling CTS |
| 171102010 | Rehabilitation following lumbar disc surgery | Lumbosacraal radiculair syndroom | Nabehandeling/ revalidatie/ werkhervatting > Postoperatieve nabehandeling van LRS |
| 171102018 | Early levodopa in Parkinson’s disease | Parkinson | Medicamentie ongecompliceerde fase ZvP > Levodopa ongecompliceerde fase ZvP |
Obstetrie en Gynaecologie (NVOG)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852002128 | ACCEPT (ACcuracy, Cost Effectivenss of Prediction models for ovarian Tumors): a study on the cost-effectiveness of risk scoring models for the discrimination between benign or malignant ovarian tumors. | 1. Het vergrote ovarium | 1. Diagnostische modellen 2. Diagnostiek > beeldvormend onderzoek" |
| 852001932 | Tubal flushing with oil-based contrast during HSG in subfertile women: Is early flushing cost-effective as compared to delayed flushing? | Oriënterend fertiliteitsonderzoek (OFO) | Hysterosalpingografie bij OFO |
| 843001805 | Evaluation of effectiveness of the PlasmaJet Surgical device in the treatment of Advanced Stage Ovarian Cancer: a randomized controlled trial in The Netherlands (PlaComOv-study) | Epitheliaal ovariumcarcinoom | Behandeling hoog stadium (IIb - IV) Chirurgie (hoog stadium) |
| 843002809 | Clinical impact of dedicated MR staging of ovarian cancer patients | Epitheliaal ovariumcarcinoom | Diagnostiek > Beeldvormend onderzoek |
| 843002821 | Evaluation of two vaginal, uterussparing surgical methods for pelvic organ prolapse reconstruction: modified Manchester operation (MM) and sacrospinal hysteropexy (SSH) | Prolaps | Chirurgische behandeling vaginale prolaps |
| 843001710 | Cost-effectiveness of a Non-degradable Urethral Bulking Agent as compared to Mid-urethral Sling surgery in women with Stress Urinary Incontinence | Urine-incontinentie (UI) bij vrouwen | UI Chirurgische behandeling > UI Interventies bij stressincontinentie |
| 843002701 | Long term effects of multidisciplinary assessment and pre- and post partum Pelvic Floor Muscle Group Treatment in primi gravid with stress urinary incontinence compared to care-as-usual: a randomised controlled trial | Urine-incontinentie (UI) bij vrouwen | UI Fysiotherapie |
| 843001602 | Embryo selection using time-lapse monitoring in IVF and ICSI patients (SelecTIMO) | Subfertiliteit | Startpagina |
| 843001605 | The CoSy-trial: Internet-based sex Counseling and chances on natural conception in couples with idiopathic Subfertility: a randomized clinical trial | Onverklaarde subfertiliteit | Startpagina |
| 843002601 | Does endometrial scratching in women with implantation failure after a first IVF/ICSI cycle lead to lower costs due to a reduction in the number of subsequent IVF/ICSI cycles needed to achieve a live birth? | Subfertiliteit | Startpagina |
| 843002603 | Procedural sedation for hysteroscopic myomectomy: cost-effectiveness and patient preference | Hevig menstrueel bloedverlies (HMB) | HMB: Poliklinische hysteroscopie |
| 843002605 | The costeffectiveness of double layer closure of the caesarean (uterine) scar in the prevention of gynaecological symptoms in relation to niche development | Indicatiestelling sectio caesarea | Startpagina |
| 843004102 | GERiatric Screening in the treatment of elderly patients with Ovarian Carcinoma (GERSOC) | Epitheliaal ovariumcarcinoom | Startpagina |
| 837001504 | Is Hysterosalpingo Foam Sonography (HyFoSy) a cost-effective alternative for hysterosalpingography (HSG) in assessing tubal patency in subfertile women? | Oriënterend fertiliteitsonderzoek (OFO) | Hysterosalpingografie bij OFO |
| 837002525 | Pessary or surgery for symptomatic pelvic organ prolapse | Prolaps | Pessariumtherapie bij prolaps |
| 837002003 | Cost-effectiveness of IUI, IVF and ICSI for male subfertility. The MAle Subfertility Therapy Effectiveness Rcts (MASTER) | Mannelijke subfertiliteit | Startpagina |
| 837003004 | Guideline-concordant care instead of the non-curative use of absorbent products in women aged 55 years and over with urinary incontinence | Urine-incontinentie bij vrouwen | UI Rol van de (continentie) verpleegkundige |
| 837004023 | Intrauterine insemination for unexplained or mild male subfertility | 1. Mannelijke subfertiliteit 2. Onverklaarde subfertiliteit | 1. Startpagina 2. Startpagina |
| 171202001 | RCT comparing the levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation.(MIRA) | Hevig menstrueel bloedverlies (HMB) | HMB: Behandelingen - Alternatieven voor hysterectomie - Ablatie versus LNG-IUD |
| 171202004 | Does switching treatment to FSH and / or IUI lead to higher pregnancy rates in a subset of women with polycystic ovary syndrome not conceiving after six ovulatory cycles with Clomiphene citrate – a randomized controlled trial | Anovulatie en kinderwens | Startpagina |
| 171102012 | HYpertension and Preeclampsia Intervention Trial in the Almost Term Patient (HYPITAT-2 study) | Hypertensieve aandoeningen in de zwangerschap | Antihypertensiva bij hypertensieve aandoening |
| 171102021 | Towards a cost-effective diagnostic work-up for women with ovarian carcinoma | Epitheliaal ovariumcarcinoom | Behandeling hoog stadium (IIb - IV) > Chirurgie (hoog stadium) |
| 843002825 | Dutch TRUFFLE: the UmbilicoCerebral Ratio in late preterm Fetal Growth Restriction | Foetale groeibeperking | Rol Doppler van ACM bij FGR na 32 weken |
| 94507203 | Multicentered Randomized Controlled Trial to Test the Cost Effectiveness of Urodynamics in women with symptoms of Stress Urinary Incontinence in whom surgical treatment is considered | Urine-incontinentie bij vrouwen | UI Urodynamisch onderzoek |
Oogheelkunde (NOG)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 843004111 | Cost-effectiveness of immediately versus delayed sequential bilateral cataract surgery (ISBCS vs. DSBCS) | Cataract | Tijdsbestek tussen twee cataractoperaties |
| 171001011 | Toric intraocular lenses: a cost-effective treatment for astigmatism in cataract surgery? | Cataract | Intra-oculaire lenzen bij cataractoperatie |
Orthopedie (NOV)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852002129 | "Active Monitoring versus an Abduction Device for treatment of Infants with Centered Dysplastic Hips, a RCT (TReatment with Active Monitoring (TRAM)-Trial)" | DDH (dysplastische heupontwikkeling) bij kinderen onder één jaar | Behandeling van stabiele DDH |
| 852002001 | The THumb osteoarthritis Exercise TriAl (THETA); a multicenter, randomized controlled trial on exercise therapy with an orthosis compared to an orthosis alone in patients with thumb base osteoarthritis | Primaire artrose van de duimbasis | Conservatieve behandeling duimbasisartrose > Effect van fysiotherapeutische interventies |
| 852002021 | How should we treat a patient with a distal radius fracture after closed reduction? A cluster RCT | Distale radius fracturen | Conservatieve behandeling van radiusfractuur > Behandeling van gedisloceerde radiusfractuur |
| 852002032 | Which patient with an anterior cruciate ligament rupture will need a surgical reconstruction? | Voorste kruisbandletsel | Indicatie Voorste Kruisbandreconstructie > Indicaties behandeling VKB-letsel |
| 852001929 | Cost-effectiveness of a transmural integrated care program for knee arthroplasty patients in the working population | Totale knieprothese | Randvoorwaarden nazorg patiënten bij TKP |
| 852001943 | Cost-effectiveness analysis of non-surgical treatment versus total knee replacement in patients with knee osteoarthritis | Totale knieprothese | Optimale indicatiestelling voor plaatsen TKP > Indicatiestelling voor plaatsen TKP |
| 853001101 | Socio-economic impact of motivational interviewing on adherence to orthopaedic shoes | Diabetische voet | Preventie > Uitvoering voetcontrole |
| 843004101 | LEAK-study LEakage After primary Knee and hip arthroplasty; finding the best way to treat wound leakage after primary arthroplasty A prospective nationwide multicenter randomised controlled trial. | 1. totale knieprothese 2. totale heupprothese | 1. Routinematige follow-up bij knieprothese 2. Startpagina |
| 843004112 | Surgical Approach of Hemiarthroplasty after Femoral Neck Fracture: Posterolateral or Direct Lateral (APOLLO) | Proximale femurfracturen | Optimale techniek proximale femurfractuur > Chirurgie en prothese collum femoris fractuur |
| 843004120 | The frail institutionalized elderly patient with a hip fracture in the shade of life (FRAIL-HIP); how do we value non-operative management? | Behandeling kwetsbare ouderen bij chirurgie | Proximale femurfractuur preoperatieve traject > Besluitvorming bij proximale femurfractuur |
| 837002404 | Should a traumatic meniscal tear be resected? | Artroscopie van de knie | Behandeling van meniscusletsels |
| 837002009 | Cost-effectiveness of Early Surgery versus Conservative Treatment with Optional Delayed Meniscectomy for Patients over 50 years. A Randomized Controlled Trial. | Artroscopie van de knie | Behandeling van meniscusletsels |
| 837004022 | The cost-effectiveness of surgery versus casting for elderly patients with intra-articular distal radius fractures. | Distale radius fracturen | Chirurgische behandeling van radiusfractuur > Indicatie aanvullende fixatie radiusfractuur |
| 171102001 | Treatment with low molecular weight heparin after knee arthroscopy and lower leg immobilisation | Artroscopie van de knie | Organisatie van zorg rond artroscopie knie |
| 171102006 | Cost-effectiveness of two treatment strategies of an anterior cruciate ligament rupture. A randomized clinical study. | Voorste kruisbandletsel | Indicatie Voorste Kruisbandreconstructie > Optimale timing voor operatie VKB |
Psychiatrie (NVvP)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 2020006341 | Efficacy and cost-effectiveness of oral esketamine versus electroconvulsive therapy for patients with severe, non-psychotic treatment resistant depression. | Depressie | Chronische en therapieresistente depressie > biologische behandelingen bij depressie |
| 852002130 | VRelax! Virtual Reality stress-reduction for burn-out, depression and anxiety. | 1. Depressie 2. Angststoornissen | 1. Eerste-stap interventies bij depressie > Bibliotherapie, zelfhulp en zelfmanagement 2. Paniekstoornis > Eerste stap interventies paniekstoornis |
| 852002103 | Efficacy of repetitive transcranial magnetic stimulation in patients with medication-resistant bipolar depression | Bipolaire stoornissen | Overige biologische behandelingen |
| 852002022 | Adjunctive physical exercise to improve psychological and pharmacological treatment outcomes in major depressive disorder: cost-effectiveness analysis alongside a randomised comparison of usual care versus enhanced care | Depressie | Eerste-stap interventies bij depressie > Fysieke inspanning, lichamelijke activiteit |
| 852002025 | Effectiveness and cost-effectiveness of internet-based treatment of insomnia in depressed patients treated at a mental healthcare institution | Depressie | Psychologische interventies depressie > Duurzaam effectieve interventies depressie |
| 852001905 | Cognitive control training (CCT) as an add-on intervention in elderly depressed patients | Depressie | Psychologische interventies depressie > Duurzaam effectieve interventies depressie |
| 852001925 | Cost-effectiveness of rTMS/CBT as next step in antidepressant non-responders. A randomized comparison with current stepped care approaches to major depressive disorder | Depressie | Farmaco-therapeutische behandeling depressie > Medicamenteuze vervolgstappen bij non-respons |
| 843001803 | Enhancing full recovery in patients with bipolar disorder | Bipolaire stoornissen | Psychosociale interventies bipolaire stoornis |
| 843002803 | Mindfulness Based Cognitive Therapy for bipolar disorder. | Bipolaire stoornissen | Psychosociale interventies bipolaire stoornis |
| 843001703 | Treatment effects and cost-effectiveness of Autonomy Enhancing Treatment: A person-centred approach to anxiety disorders. | Angststoornissen | Gegeneraliseerde angststoornis (GAS) > Psychologische interventie bij GAS > Cognitieve therapie bij GAS |
| 843001704 | Walk and Talk; A Randomized Controlled Trial of High Intensive Treatment versus Care as Usual for Posttraumatic Stress Disorder. | Angststoornissen | Inleiding PTSS > Inleiding Psychologische interventies PTSS > Trauma-gerichte cognitieve gedragstherapie |
| 843001705 | Cost effectiveness of trauma-focused treatments for childhood-related Posttraumatic Stress Disorder in adults | Angststoornissen | Inleiding PTSS > Inleiding Psychologische interventies PTSS > Trauma-gerichte cognitieve gedragstherapie |
| 843001706 | Group schema-focussed therapy enriched with psychomotor therapy for older adults with personality disorders in specialized mental health care. | Persoonlijkheids-stoornissen | AS II Psychotherapeutische interventies |
| 843002709 | Economic evaluation of psychiatric rehabilitation/self-management group intervention (PPEP4All) compared with usual care in patients with Persistent Depressive Disorder (PDD) and their partner; a multicenter pragmatic randomized controlled trial | Depressie | Chronische en therapieresistente depressie > Rehabilitatie en reïntegratie bij depressie |
| 843001604 | Changing perspectives: Cost-Effectiveness of Interpretation Bias Modification in patients with Major Depressive Disorder | Depressie | Psychologische interventies depressie > Effect psychotherapeutische behandelingen |
| 843001608 | Internet-based attentional bias modification training as add-on to regular treatment in alcohol or cannabis dependent outpatients. | Stoornissen in het gebruik van alcohol | Alcohol - Psychosociale interventies > Alcohol - Cognitieve gedragsinterventies |
| 837001401 | Cognitive Behavioural Therapy focussing on Social Activation in Patients with Recent Onset Schizophrenia. | Schizofrenie | Psychosociale interventies bij schizofrenie > Effect cognitieve gedragstherapie schizofrenie |
| 837002401 | Frequency of psychotherapy sessions for depression: a multicenter randomized trial | Depressie | Psychologische interventies depressie > Benodigde therapieduur bij depressie |
| 837001004 | Cognitive Remediation Therapy as a treatment enhancer in eating disorders and obsessive compulsive disorders | Angststoornissen | Obsessief-compulsieve stoornis (OCS) > Psychologische interventies OCS > Cognitieve therapie compulsieve stoornis |
| 837001007 | Blended Care for Depression in Secondary Care | Depressie | Eerste-stap interventies bij depressie > E-health bij depressie |
| 171201008 | Effectiveness of Deep Brain Stimulation in therapy resistant depressive disorder in the Netherlands. Effects, tolerability and cost-effectiveness relative to treatment as usual. | Depressie | Chronische en therapieresistente depressie > Biologische behandelingen bij depressie |
| 171202009 | Group Schema Therapy for Borderline Personality Disorder | Persoonlijkheids-stoornissen | AS II Psychotherapeutische interventies > AS II Ambulante psychotherapie borderline |
| 171202012 | Day hospital Mentalization-Based treatment versus Intensive Outpatient Mentalization-Based Treatment for patients with severe borderline personality disorder: A multi-centre head-to-head randomized clinical trial | Persoonlijkheids-stoornissen | AS II Psychotherapeutische interventies > AS II Dosering en wijze van toepassing |
| 171102002 | The effects and costs of preventive cognitive therapy plus usual care for remitted primary care patients with major depression versus usual care | Depressie | Voorkomen van terugval bij depressie > Preventie terugval psychotherapie depressie |
| 171102003 | Cost-effectiveness of internet-based guided self-help for depressive disorders in specialized mental health care: A randomized controlled trial | Depressie | Eerste stap interventies bij depressie > E-health bij depressie |
| 171102004 | Reducing relapse and recurrence in depression with continuation Cognitive Therapy: a randomized controlled trial | Depressie | Voorkomen van terugval bij depressie > Preventie terugval psychotherapie depressie |
| 171102013 | Gut-directed hypnotherapy in children with irritable bowel syndrome: self exercises at home using recorded scripts on CD versus individual therapy by qualified therapists. | SOLK en somatoforme stoornissen | SOLK Prikkelbaredarmsyndroom > SOLK Psychologische methoden bij PDS |
| 171001002 | Active mobilisation of psychological resources during passive antidepressant pharmacotherapy (Name study: REsource MObilisation Device In Depression (REMOD-ID)) | Depressie | Combinatiebehandeling bij depressie |
| 171001007 | D-cycloserine enhancement of exposure and response prevention (ERP) therapy in OCD and panic disorder with agoraphobia: a randomized controlled trial | Angststoornissen | Obsessief-compulsieve stoornis (OCS) > Psychologische interventies OCS > Exposure in vivo compulsieve stoornis |
| 171001010 | Metacognitive training: a randomized controlled trial to evaluate efficacy and cost-effectiveness of a training that aims to change cognitive biases that perpetuate psychosis in people with paranoid schizophrenia | Schizofrenie | Psychosociale interventies bij schizofrenie > Effect cognitieve gedragstherapie schizofrenie |
| 171002401 | Cost-effectiveness of cognitive therapy with tapering of AD versus continuation of maintenance antidepressant treatment and the combination of both in preventing relapse and recurrence in recurrent depression: a randomized controlled multi-center trial | Depressie | Voorkomen van terugval bij depressie > Preventie terugval psychotherapie depressie |
| 171002402 | Mentalisation-Based Treatment versus care-as-usual in the treatment of severe borderline personality disorders | Persoonlijkheids-stoornissen | AS II Psychotherapeutische interventies > AS II Dagklinische psychotherapie breed |
| 171002403 | Cost effectiveness of an E-health module on Return to Work embedded in collaborative occupational health care for depressive disorders | Depressie | Maatschappelijke participatie bij depressie |
| 170992903 | The clinical and cost-effectiveness of mindfulness based cognitive therapy, maintenance antidepressant medication and its combination in the prevention of relapse in patients with recurrent depression. | Depressie | Voorkomen van terugval bij depressie |
Radiologie (NVvR)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 843001801 | Rapid Access to Contrast-Enhanced spectral mammogRaphy (RACER): a more efficient work-up of women recalled from breast cancer screening | Borstkanker | Diagnostiek > Mammografie en echografie |
| 843002823 | Cost-effective diagnostic evaluation of patients with symptomatic breast disease; ultrasound as accurate initial imaging technique | Borstkanker | Diagnostiek > Mammografie en echografie |
| 843004105 | Risk assessment and MR imaging in prostate cancer diagnosis: an impact analysis | Prostaatcarcinoom | Diagnostiek > Beeldvormend onderzoek > MRI-geleide biopten |
| 843004121 | Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in The Netherlands for Late arrivals: MR CLEAN-LATE | Herseninfarct en hersenbloeding | Reperfusietherapie voor acute herseninfarct > Endovasculaire behandeling herseninfarct |
Radiotherapie en Oncologie (NVRO)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852001923 | Clinical effectiveness and cost-effectiveness of prophylactic cranial irradiation (PCI) for radically treated stage III non-small cell lung cancer: A meta-analysis on updated individual patient data of randomized phase III trials | Niet kleincellig longcarcinoom | Stadium III-NSCLC |
| 843004015 | Substantiële verbetering van de overleving van stadium III, BRCA1-like borstkanker patiënten met doelgerichte behandeling | Borstkanker | Adjuvante chemotherapie > Adjuvante systemische therapie |
| 171201001 | Diffusion-weighted MR imaging to improve the selection of good and complete responders after chemoradiation therapy in rectal cancer | Colorectaal carcinoom | Primaire behandeling rectumcarcinoom > Neoadjuvante therapie lokaal gevorderd RC |
| 171002211 | Design and analysis of a stepped wedge cluster randomized design | Colorectaal carcinoom | Primaire behandeling coloncarcinoom > Follow-up na oncologische segmentresectie CC |
Reumatologie (NVR)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 94517103 | Implementation of screening and treatment of high-risk fracture patients by an osteoporosis nurse-practitioner. | Osteoporose en fractuurpreventie | Diagnostiek osteoporose en fractuurpreventie > Organisatie van zorg osteoporose |
Revalidatiegeneeskunde (VRA)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 852002024 | Outcome and cost-effectiveness of a dynamic Lucerne-cast versus immobilization by forearm-cast in patients with FraCtures (neck, sHaft, intra-Articular) of the MetacarPAl bone, requirinG Non-operative trEatment. SHORT-TITLE: CHAMPAGNE-study | Handfracturen | Fracturen van de metacarpalia |
| 170995003 | Quality of life, gross motor function, and actual everyday physical activity level in children with spastic Cerebral Palsy: (cost)effectiveness of combined treatment with multilevel botulinum-toxin injections and intensive functional physiotherapy. | Spastische cerebrale parese bij kinderen | Behandeling gericht op verbetering mobiliteit > Effect van botulinetoxine-A op lopen bij CP |
Urologie (NVU)
| Dossiernummer | Projecttitel ZonMw | Richtlijn | Module |
|---|---|---|---|
| 152001014 | Impact of new approaches to pharmacological management of patients with renal cell carcinoma: a population-based study of process and outcomes in The Netherlands. | Niercelcarcinoom | Lokaal recidief/ metastasen behandeling > Systemische therapie > eerstelijns therapie |